Antonio Bedalov

Appointments and Affiliations
 
 
Fred Hutchinson Cancer Research Center
Clinical Research Division
Associate Member, Appointed: 2010
University of Washington
School of Medicine
School of Medicine
Associate Professor, Appointed: 2010
University of Washington Medical Center
Medicine
Attending Physician, Appointed: 1999
 Professional Headshot of Antonio Bedalov

Mailing Address

1100 Fairview Ave. N.
P.O. Box 19024
Mailstop D2-190
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-4863
Fax: (206) 667-6519
http://labs.fhcrc.org/bedalov/index.html

Degrees

Ph.D., University of Zagreb, Medical Sciences, 1998.
M.D., University of Zagreb, 1989.

Memberships

American Board of Internal Medicine
American Board of Medical Oncology

Honors and Awards

2002-2006, Ellison Medical Foundation New Scholar, Ellison Medical Foundation
1998, Mentored Clinical Scientist Development Award (KO8), National Heart Lung and Blood Institute, Fred Hutchinson Cancer Research Center
1992, American Heart Association Fellowship Award, American Heart Association (AHA), Fred Hutchinson Cancer Research Center

Previous Positions

2004-2010, Assistant Member, Fred Hutchinson Cancer Research Center, Clinical Research Division, Clinical Research
2004-2010, Assistant Professor, University of Washington, School of Medicine, Medicine
1999-2004, Acting Instructor, University of Washington, School of Medicine, Medicine
1999-2004, Associate, Fred Hutchinson Cancer Research Center, Clinical Research
1997-1999, Senior Fellow, Fred Hutchinson Cancer Research Center, Clinical Research
1996-1997, Hematology/Oncology Fellow, Clinical Rotations, University of Washington, School of Medicine
1993-1996, Resident, The Texas A&M Health Science Center, Baylor College of Medicine, Internal Medicine
1990-1993, Postdoctoral Fellow, University of Connecticut, Health Center

 

Recent Publications

2013
Kwan, EX, Foss EJ, Tsuchiyama S, Alvino GM, Kruglyak L, Kaeberlein M, Raghuraman MK, Brewer BJ, Kennedy BK, Bedalov A.  2013.  A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan.. PLoS genetics. 9(3):e1003329. Abstract
Banfic, H, Bedalov A, York JD, Visnjic D.  2013.  Inositol pyrophosphates modulate S phase progression after pheromone-induced arrest in Saccharomyces cerevisiae.. The Journal of biological chemistry. 288(3):1717-25. Abstract
2012
Foss, EJ, Radulovic D, Stirewalt DL, Radich J, Sala-Torra O, Pogosova-Agadjanyan EL, Hengel SM, Loeb KR, Deeg HJ, Meshinchi S et al..  2012.  Proteomic Classification of Acute Leukemias by Alignment-Based Quantitation of LC-MS/MS Data Sets.. Journal of proteome research. 11(10):5005-10. Abstract
Leko, V, Varnum-Finney B, Li H, Gu Y, Flowers D, Nourigat C, Bernstein ID, Bedalov A.  2012.  SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.. Blood. 119(8):1856-1860. Abstract
2011
Burnett, C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ et al..  2011.  Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.. Nature. 477(7365):482-5. Abstract
Foss, EJ, Radulovic D, Shaffer SA, Goodlett DR, Kruglyak L, Bedalov A.  2011.  Genetic variation shapes protein networks mainly through non-transcriptional mechanisms.. PLoS biology. 9(9):e1001144. Abstract
Nemecek, ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Marshall, GM, Liu P-Y, Gherardi S, Scarlett CJ, Bedalov A, Xu N, Iraci N, Valli E, Ling D, Thomas W et al..  2011.  SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.. PLoS genetics. 7(6):e1002135. Abstract
Kwan, EX, Foss E, Kruglyak L, Bedalov A.  2011.  Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast.. PLoS genetics. 7(8):e1002250. Abstract
Mahajan, SS, Leko V, Simon JA, Bedalov A.  2011.  Sirtuin modulators.. Handbook of experimental pharmacology. (206):241-55. Abstract
2009
Van Gool, F, Gallí M, Gueydan C, Kruys V, Prevot P-P, Bedalov A, Mostoslavsky R, Alt FW, De Smedt T, Leo O.  2009.  Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner.. Nature medicine. 15(2):206-10. Abstract
Newcomb, B, Bedalov A.  2009.  Identification of inhibitors of chromatin modifying enzymes using the yeast phenotypic screens.. Methods in molecular biology (Clifton, N.J.). 548:145-60. Abstract
2008
Chevillet, JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI.  2008.  Identification and characterization of small-molecule inhibitors of hepsin.. Molecular cancer therapeutics. 7(10):3343-51. Abstract
Arnoldo, A, Curak J, Kittanakom S, Chevelev I, Lee VT, Sahebol-Amri M, Koscik B, Ljuma L, Roy PJ, Bedalov A et al..  2008.  Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.. PLoS genetics. 4(2):e1000005. Abstract