John J. Crowley

Appointments and Affiliations

 
 
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Program in Biostatistics
Member
University of Washington
School of Public Health and Community Medicine
Biostatistics
Professor
Professional Headshot of John J. Crowley

Mailing Address

Southwest Oncology Group Statistical Center
Fred Hutchinson Cancer Research Center MP-557
1100 Fairview Ave N, PO Box 19024
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-4623
Fax: (206) 667-4408

Degrees

Ph.D., University of Washington, 1973.
M.S., 1970.

Research Interests

Design And Analysis Of Cancer Clinical Trials.

The Southwest Oncology Group (SWOG) is a national consortium of institutions and investigators whose mission is to make progress in the prevention and cure of cancer through clinical research. The Statistical Center, located in the Division of Public Health Sciences of the FHCRC, contributes to this mission through study design, protocol development, data management and quality control, data analysis, and statistical research.

SWOG has over 100 trialsopen for patient accrual in all sites of cancer, plus a large prostate cancer prevention trial. Recent advances have been made in the treatment of ovarian, bladder, prostate, lung, colon, and head and neck cancers. The Statistical Center's efforts are carried out by a staff of over 65 people, including eight faculty biostatisticians and a behavioral scientist.

My own emphasis within SWOG is in lung cancer and multiple myeloma. In addition to the design and analysis of trials in these disease sites,including a randomized study of high dose therapy and autologous transplantation in myeloma, I have been involved in assessing the importance of various laboratory findings in predicting survival and forming prognostic groups. My longstanding interest in developing exploratory tools for survival data has found fruitful application in these areas. My other current interest is in the education of cancer clinicians in the principles and pitfalls of cancer clinical trials.

 

Recent Publications

2013
Detterbeck, FC, Asamura H, Crowley J, Falkson C, Giaccone G, Giroux D, Huang J, Kim J, Kondo K, Lucchi M et al..  2013.  The IASLC/ITMIG Thymic Malignancies Staging Project: Development of a Stage Classification for Thymic Malignancies.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 8(12):1467-73. Abstract
2012
2011
Hoering, A, LeBlanc M, Crowley J.  2011.  Seamless phase I-II trial design for assessing toxicity and efficacy for targeted agents.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17(4):640-6. Abstract
2010
Ludwig, H, Bolejack V, Crowley J, Bladé J, Miguel JS, Kyle RA, Rajkumar VS, Shimizu K, Turesson I, Westin J et al..  2010.  Survival and years of life lost in different age cohorts of patients with multiple myeloma.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(9):1599-605. Abstract