Chad (Qianchuan) He
Appointments and Affiliations
Ph.D., Biostatistics, University of North Carolina, 2012.
Ph.D., Microbiology and Molecular Genetics, Michigan State University, 2005.
M.S., Statistics, Michigan State University, 2004.
B.S., Biology, Beijing University, 1997.
My research is focused on the development of new statistical methods to tackle the high-dimensionality of genomic data. This includes variable selection, dimension reduction and risk prediction for high-throughput genetic studies. I am also interested in multivariate-outcome data analysis, machine learning and quantile regression methods.
American Statistics Association
Eastern North American Region of the International Biometric Society
Honors and Awards
Finalist for NIH Director's Early Independence Award, 2013
Young Investigator Award, Section on Statistics in Epidemiology, American Statistical Association, 2013
ENAR Distinguished Student Paper Award, 2012
NIH Research Fellowship, 2005-2006
Graduate Student Research Enhancement Award, Michigan State University, 2003
Ronald M. and Sharon Rogowski Fellowship, Michigan State University, 2003
A Web-Server of Cell Type Discrimination System. Scientific World Journal.. 2014.
Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.. Proceedings of the National Academy of Sciences of the United States of America. 110(37):15043-8.. 2013.
Fasting insulin concentrations and incidence of hypertension, stroke, and coronary heart disease: a meta-analysis of prospective cohort studies.. The American journal of clinical nutrition. 98(6):1543-54.. 2013.
A general framework for association tests with multivariate traits in large-scale genomics studies.. Genetic epidemiology. 37(8):759-67.. 2013.
PEGylation is effective in reducing immunogenicity, immunotoxicity, and hepatotoxicity of α-momorcharin in vivo.. Immunopharmacology and immunotoxicology.. 2012.
Alpha-momorcharin possessing high immunogenicity, immunotoxicity and hepatotoxicity in SD rats.. Journal of ethnopharmacology. 139(2):590-8.. 2012.
Fine-mapping and initial characterization of QT interval loci in African Americans.. PLoS genetics. 8(8):e1002870.. 2012.
Common genetic variation in adiponectin, leptin, and leptin receptor and association with breast cancer subtypes.. Breast cancer research and treatment. 129(2):593-606.. 2011.
A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.. PLoS genetics. 7(10):e1002322.. 2011.
A variable selection method for genome-wide association studies.. Bioinformatics (Oxford, England). 27(1):1-8.. 2011.
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo.. Molecular psychiatry. 14(4):359-75.. 2009.
Inherited motor neuron disease in domestic cats: a model of spinal muscular atrophy.. Pediatric research. 57(3):324-30.. 2005.
Canine Imerslund-Gräsbeck syndrome maps to a region orthologous to HSA14q.. Mammalian genome : official journal of the International Mammalian Genome Society. 14(11):758-64.. 2003.
Congenital hypothyroidism with goiter in toy fox terriers.. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 17(1):50-7.. 2003.