Holly Janes

Appointments and Affiliations
 
 
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Program in Biostatistics and Biomathematics
Assistant Member, Appointed: 2007
 Professional Headshot of Holly Janes

Mailing Address

1100 Fairview Ave N
M2-C200
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-6353
Fax: (206) 667-4378
hjanes@scharp.org

Degrees

Ph.D., University of Washington, Biostatistics, 2005.
M.A., University of Massachusetts at Amherst, Mathematics, 2000.
B.A., Skidmore College, Philosophy of Physical Science and Mathematical Modeling, 1998.

Honors and Awards

2008, Travel Award, Global HIV Vaccine Enterprise, AIDS Vaccine Conference
2006, Young Investigator Award, Section on Statistics in Epidemiology, American Statistical Association
2005, Gilbert S. Omenn Graduate Student Award for Academic Excellence, School of Public Health, University of Washington
2005, Student Conference Award, International Society for Clinical Biostatistics
2005, Senior Student Award, Department of Biostatistics, University of Washington
2004, Student Paper Award, Section on Statistics and the Environment, American Statistical Association
2000, Cardiovascular Biostatistics Training Grant, National Institutes of Health

Previous Positions

2005-2007, Postdoctoral Fellow, Johns Hopkins School of Public Health, Biostatistics
2002-2005, Research Assistant, UW/EPA NW Research Center for Particulate Air Pollution and Health
2002-2003, Research Assistant, Fred Hutchinson Cancer Research Center, Division of Public Health Sciences

 

Recent Publications

2013
Abu-Raddad, LJ, Barnabas RV, Janes H, Weiss HA, Kublin JG, Longini IM, Wasserheit JN.  2013.  Have the explosive HIV epidemics in sub-Saharan Africa been driven by higher community viral load? AIDS (London, England). 27(6):981-89. Abstract
Janes, H.  2013.  Letter to the editor.. Biostatistics (Oxford, England).
Janes, H, Gilbert P, Buchbinder S, Kublin J, Sobieszczyk ME, Hammer SM.  2013.  In Pursuit of an HIV Vaccine: Designing Efficacy Trials in the Context of Partially Effective Non-Vaccine Prevention Modalities.. AIDS research and human retroviruses. Abstract
Janes, H, Pepe M.  2013.  Re: "Clinical Usefulness of the Framingham Cardiovascular Risk Profile beyond Its Statistical Performance: The Tehran Lipid and Glucose Study".. American journal of epidemiology. 177(8):864-5.
2012
Huang, Y, Gilbert PB, Janes H.  2012.  Assessing Treatment-Selection Markers using a Potential Outcomes Framework.. Biometrics. 68(3):687-696. Abstract
Haynes, BF, Gilbert PB, McElrath MJ, Zolla-Pazner S, Tomaras GD, Alam MS, Evans DT, Montefiori DC, Karnasuta C, Sutthent R et al..  2012.  Immune-correlates analysis of an HIV-1 vaccine efficacy trial.. The New England journal of medicine. 366(14):1275-86. Abstract
Janes, H, Frahm N, DeCamp A, Rolland M, Gabriel E, Wolfson J, Hertz T, Kallas E, Goepfert P, Friedrich DP et al..  2012.  MRKAd5 HIV-1 Gag/Pol/Nef Vaccine-Induced T-Cell Responses Inadequately Predict Distance of Breakthrough HIV-1 Sequences to the Vaccine or Viral Load.. PloS one. 7(8):e43396. Abstract
2011
Janssens, CAJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J et al..  2011.  Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.. European journal of clinical investigation. 41(9):1010-1035. Abstract
Janssens, CAJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J et al..  2011.  Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.. European journal of human genetics : EJHG. 19(5):18ppreceding494. Abstract
Fitzgerald, DW, Janes H, Robertson M, Coombs R, Frank I, Gilbert PB, Loufty M, Mehrotra D, Duerr A.  2011.  An Ad5-vectored HIV-1 vaccine elicits cell-mediated immunity but does not affect disease progression in HIV-1-infected male subjects: results from a randomized placebo-controlled trial (the Step study).. The Journal of infectious diseases. 203(6):765-72. Abstract
Barnabas, RV, Wasserheit JN, Huang Y, Janes H, Morrow RA, Fuchs J, Mark KE, Casapia M, Mehrotra DV, Buchbinder SP et al..  2011.  Impact of Herpes Simplex Virus Type 2 on HIV-1 Acquisition and Progression in an HIV Vaccine Trial (the Step Study).. Journal of acquired immune deficiency syndromes (1999). 57(3):238-244. Abstract
Janes, H, Pepe MS, Bossuyt PM, Barlow WE.  2011.  Measuring the performance of markers for guiding treatment decisions.. Annals of internal medicine. 154(4):253-9. Abstract
Pepe, MS, Janes H.  2011.  Commentary: Reporting standards are needed for evaluations of risk reclassification.. International journal of epidemiology. 40(4):1106-8.
Janssens, CAJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J et al..  2011.  Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration.. Journal of clinical epidemiology. 64(8):e1-e22. Abstract
Janssens, CAJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J et al..  2011.  Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.. European journal of epidemiology. 26(4):313-37. Abstract
2010
Janes, H, Dominici F, Zeger S.  2010.  On quantifying the magnitude of confounding.. Biostatistics (Oxford, England). 11(3):572-82. Abstract
Seaman, MS, Janes H, Hawkins N, Grandpre LE, Devoy C, Giri A, Coffey RT, Harris L, Wood B, Daniels MG et al..  2010.  Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies.. Journal of virology. 84(3):1439-52. Abstract
2009
Pepe, MS, Longton G, Janes H.  2009.  Estimation and Comparison of Receiver Operating Characteristic Curves.. The Stata journal. 9(1):1. Abstract
Janes, H, Longton G, Pepe MS.  2009.  Accommodating Covariates in ROC Analysis.. The Stata journal. 9(1):17-39. Abstract
2008
Pepe, MS, Feng Z, Janes H, Bossuyt PM, Potter JD.  2008.  Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design.. Journal of the National Cancer Institute. 100(20):1432-8. Abstract
Janes, H, Sheppard L, Shepherd K.  2008.  Statistical analysis of air pollution panel studies: an illustration.. Annals of epidemiology. 18(10):792-802. Abstract
McElrath, MJ, De Rosa SC, Moodie Z, Dubey S, Kierstead L, Janes H, Defawe OD, Carter DK, Hural J, Akondy R et al..  2008.  HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis.. Lancet. 372(9653):1894-905. Abstract
Janes, H, Pepe MS, Gu W.  2008.  Assessing the value of risk predictions by using risk stratification tables.. Annals of internal medicine. 149(10):751-60. Abstract
Janes, H, Pepe MS.  2008.  Matching in studies of classification accuracy: implications for analysis, efficiency, and assessment of incremental value.. Biometrics. 64(1):1-9. Abstract
Pepe, MS, Janes H.  2008.  Gauging the performance of SNPs, biomarkers, and clinical factors for predicting risk of breast cancer.. Journal of the National Cancer Institute. 100(14):978-9.