Ph.D., University of Bonn, Nutrition Sciences, 2001.
M.Sc., University of Bonn, Nutrition Sciences, 1996.
The main interest of my group is the relationship between diet, obesity, and diseases associated with obesity. More specifically, we are investigating the molecular, metabolic, and cellular mechanisms by which increased adiposity is linked to disease, and how these processes are affected by diet.
One major focus lies on obesity-associated adipose tissue inflammation. We are interested in the cell types that infiltrate human adipose tissue, and the relationship of the resulting chronic low-grade inflammation to insulin resistance and glucose intolerance. We conduct human clinical studies to understand the effect of selected dietary factors on chronic low-grade adipose tissue and systemic inflammation.
(Reading, Writing, Speaking)
English: (Fluent, Fluent, Fluent)
German: (Fluent, Fluent, Fluent)
American Diabetes Association
American Society for Nutrition
2003-2007, Post-doctoral fellow, University of Washington, Medicine, Metabolism, Endocrinology & Nutrition
2001-2003, Post-doctoral fellow, Leibnitz-Institute of Arteriosclerosis Research
1997-2001, Ph.D. student, Leibnitz-Institute of Arteriosclerosis Research, Muenster, Germany
Comparison and validation of 2 analytical methods for measurement of urinary sucrose and fructose excretion.. Nutrition research (New York, N.Y.). 33(9):696-703.. 2013.
Effects of a high-protein diet on regulation of phosphorus homeostasis.. The Journal of clinical endocrinology and metabolism. 98(3):1207-13.. 2013.
Gene Expression Changes in Adipose Tissue with Diet- and/or Exercise-Induced Weight Loss.. Cancer prevention research (Philadelphia, Pa.). 6(3):217-31.. 2013.
n3 PUFAs Do Not Affect Adipose Tissue Inflammation in Overweight to Moderately Obese Men and Women.. The Journal of nutrition. 143(8):1340-7.. 2013.
Lifestyle factors and inflammation: associations by body mass index.. PloS one. 8(7):e67833.. 2013.
Reliability of Serum Biomarkers of Inflammation from Repeated Measures in Healthy Individuals.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.. 2012.
The relationship between high-fat dairy consumption and obesity, cardiovascular, and metabolic disease.. European journal of nutrition.. 2012.
Characterizing and quantifying leukocyte populations in human adipose tissue: Impact of enzymatic tissue processing.. Journal of immunological methods. 386(1-2):50-9.. 2012.
Changes in adipose-derived inflammatory cytokines and chemokines after successful lifestyle intervention in obese children.. Metabolism: clinical and experimental. 60(4):445-52.. 2011.
Vitamin d deficiency in obese children and its relationship to insulin resistance and adipokines.. Journal of obesity. 2011:495101.. 2011.
Increased risk of orofacial clefts associated with maternal obesity: case-control study and Monte Carlo-based bias analysis.. Paediatric and perinatal epidemiology. 24(5):502-12.. 2010.
Biomarkers of systemic inflammation and risk of incident, symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial.. American journal of epidemiology. 171(5):571-82.. 2010.
Exchanging carbohydrate or protein for fat improves lipid-related cardiovascular risk profile in overweight men and women when consumed ad libitum.. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 58(5):711-9.. 2010.
Emerging role of estrogen in the control of cardiometabolic disease.. Trends in pharmacological sciences. 31(4):183-9.. 2010.
Hypercaloric diets differing in fat composition have similar effects on serum leptin and weight gain in female subjects with anorexia nervosa.. Nutrition research (New York, N.Y.). 29(1):1-7.. 2009.
A pilot study of sampling subcutaneous adipose tissue to examine biomarkers of cancer risk.. Cancer prevention research (Philadelphia, Pa.). 2(1):37-42.. 2009.
Reduced adipogenic gene expression in thigh adipose tissue precedes human immunodeficiency virus-associated lipoatrophy.. The Journal of clinical endocrinology and metabolism. 93(3):959-66.. 2008.
Effect of dietary n-3 polyunsaturated fatty acids on plasma total and high-molecular-weight adiponectin concentrations in overweight to moderately obese men and women.. The American journal of clinical nutrition. 87(2):347-53.. 2008.
Similar serum plant sterol responses of human subjects heterozygous for a mutation causing sitosterolemia and controls to diets enriched in plant sterols or stanols.. European journal of clinical nutrition. 61(7):896-905.. 2007.
Individual serum triglyceride responses to high-fat and low-fat diets differ in men with modest and severe hypertriglyceridemia.. The Journal of nutrition. 134(6):1400-5.. 2004.
Dietary mono- and polyunsaturated fatty acids similarly increase plasma apolipoprotein A-IV concentrations in healthy men and women.. The Journal of nutrition. 133(6):1821-5.. 2003.
The impact of dietary fat composition on serum leptin concentrations in healthy nonobese men and women.. The Journal of clinical endocrinology and metabolism. 87(11):5008-14.. 2002.