Andrea Z. Lacroix
Ph.D., University of North Carolina, 1984.
Dr. Andrea LaCroix has expertise in epidemiologic methods; large randomized controlled clinical trials; osteoporosis and fracture; women's health; aging; and cardiovascular disease. Dr. LaCroix is Co-Principal Investigator of the Women's Health Initiative Clinical Coordinating Center at the Fred Hutchinson Cancer Research Center; Scientific Investigator at the Center for Health Studies, Group Health Cooperative of Puget Sound; and Professor of Epidemiology at the University of Washington in Seattle. Her research focuses on prevention of osteoporosis and fracture in women of all ages, as well as prevention of coronary disease and cancer. She has published widely on these topics with an emphasis on identifying effective pharmacologic and lifestyle interventions for healthy aging among women.
In the past year, Dr. LaCroix published the results of a three-year randomized controlled trial started in 1993 showing that low dose hydrochlorothiazide preserved bone density at the hip and spine in older adults. She also presented the results of an analysis from the Women's Health Initiative Observational Study, a prospective cohort study of 93,724 women, showing that women who took statin medications for lipid lowering had similar rates of hip, lower arm/wrist and other clinical fractures as women who did not take statin medications. These findings contrast with earlier studies showing a benefit of statins on risk of hip fracture. Dr. LaCroix and her colleagues have developed and tested a workbook designed to assist women with making informed decisions about whether or not to take hormone replacement therapy. Evaluation of the workbook with a randomized controlled trial showed significant improvements in knowledge about HRT among women who received the workbook. This document will be published in the spring 2001 catalogue of the US Government Printing Office and will also be disseminated through a website under development by the Centers for Disease Control. Dr. LaCroix is collaborating as the senior investigator on a new randomized trial testing the effects of selected herbal remedies on vasomotor symptoms, cardiovascular risk factors and bone density in symptomatic perimenopausal women.
American Heart Association
American Public Health Association
American Society for Bone and Mineral Research
Society for Epidemiologic Research
Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials.. JAMA : the journal of the American Medical Association. 310(13):1353-68.. 2013.
Sex hormone levels and risk of breast cancer with estrogen plus progestin.. Journal of the National Cancer Institute. 105(19):1496-503.. 2013.
Vitamin D intake and lung cancer risk in the Women's Health Initiative.. The American journal of clinical nutrition. 98(4):1002-11.. 2013.
Oral bisphosphonate use and colorectal cancer incidence in the Women's Health Initiative.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013.
Editorial: introducing the 2013 volume of epidemiologic reviews on aging.. American journal of epidemiology. 177(5):377-9.. 2013.
Risk factors for treatment failure with antiosteoporosis medication: The global longitudinal study of osteoporosis in women (GLOW).. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013.
A meta-analysis of the association of fracture risk and body mass index in women.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013.
Investigation of Epstein-Barr Virus as a Potential Cause of B-Cell Non-Hodgkin Lymphoma in a Prospective Cohort.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.. 2013.
Relationship of weight, height, and body mass index with fracture risk at different sites in postmenopausal women: The global longitudinal study of osteoporosis in women (GLOW).. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013.
Frailty and Fracture, Disability, and Falls: A Multiple Country Study From the Global Longitudinal Study of Osteoporosis in Women.. Journal of the American Geriatrics Society.. 2013.
Loci influencing blood pressure identified using a cardiovascular gene-centric array.. Human molecular genetics.. 2013.
Women's Health Initiative View of Estrogen Avoidance and All-Cause Mortality.. American journal of public health. 103(12):e2.. 2013.
Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial.. Menopause (New York, N.Y.).. 2013.
Efficacy of exercise for menopausal symptoms: a randomized controlled trial.. Menopause (New York, N.Y.).. 2013.
Health maintenance module improves BMD testing.. The Nurse practitioner. 38(4):37-41.. 2013.