David MacPherson

Appointments and Affiliations

Fred Hutchinson Cancer Research Center
Human Biology Division
Assistant Member, Appointed: 2012
Professional Headshot of David MacPherson

Mailing Address

Fred Hutchinson Cancer Research Center
D4-100
P.O. Box 19024
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-6464
Fax: (206) 667-2917
dmacpher@fhcrc.org
http://labs.fhcrc.org/macpherson/index.html

Degrees

Ph.D., Massachusetts Institute of Technology, Biology, 2005.
B.Sc. (Hons), McMaster University, Biology and Pharmacology, 1998.

Research Interests

Genetic and genomic analyses of cancer, mouse models of small cell lung carcinoma and retinoblastoma.

Previous Positions

2005-2012: Staff Associate, Carnegie Institution, Department of Embryology.
2000-2005: Graduate Student, Tyler Jacks Lab, Massachusetts Institute of Technology.

Honors and Awards

2011-2015: American Cancer Society Research Scholar
2004: David Koch Graduate Fellowship, Massachusetts Institute of Technology

Funding

  • NIH: Using mouse models to understand retinoblastoma initiation and progression, Principal Investigator, 08/12/2010 - 12/31/2014.
  • American Cancer Society Research Scholar Grant: Collaboration between the RB pathway and oncogenic microRNAs in cancer, 7/01/2011- 6/30/2015.
  • DoD: Investigating SKP2 as a therapeutic target for small cell lung cancer, Principal Investigator, 9/30/2014-9/29/2015
  • NIH: Interrogation of MLL2 as a tumor suppressor gene in lung cancer, Principal Investigator, 3/1/2015-2/29/2020

Recent Publications

2015
Gazdar, AF, Savage TK, Johnson JE, Berns A, Sage J, Linnoila IR, MacPherson D, McFadden DG, Farago A, Jacks T et al..  2015.  The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 10(4):553-64. Abstract
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