David MacPherson

Appointments and Affiliations

Fred Hutchinson Cancer Research Center
Human Biology Division
Assistant Member, Appointed: 2012
 Professional Headshot of David MacPherson

Mailing Address

Fred Hutchinson Cancer Research Center
D4-100
P.O. Box 19024
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-6464
Fax: (206) 667-2917
dmacpher@fhcrc.org
http://labs.fhcrc.org/macpherson/index.html

Degrees

Ph.D., Massachusetts Institute of Technology, Biology, 2005.
B.Sc. (Hons), McMaster University, Biology and Pharmacology, 1998.

Research Interests

Genetic and genomic analyses of cancer, mouse models of small cell lung carcinoma and retinoblastoma.

Previous Positions

2005-2012: Staff Associate, Carnegie Institution, Department of Embryology.
2000-2005: Graduate Student, Tyler Jacks Lab, Massachusetts Institute of Technology.
1998-1999: Research Technician, Tak Mak Lab, Ontario Cancer Institute.

Honors and Awards

2011-2015: American Cancer Society Research Scholar
2004: David Koch Graduate Fellowship, Massachusetts Institute of Technology
1994-1998: Honors, Biology Department, McMaster University

Funding

  • NIH: Using mouse models to understand retinoblastoma initiation and progression, Principal Investigator, 08/12/2010 - 12/31/2014.
  • American Cancer Society Research Scholar Grant: Collaboration between the RB pathway and oncogenic microRNAs in cancer, 7/01/2011- 6/30/2015.

Recent Publications

2012
Conkrite, K, Sundby M, Mu D, Mukai S, MacPherson D.  2012.  Cooperation between Rb and Arf in suppressing mouse retinoblastoma.. The Journal of clinical investigation. 122(5):1726-33. Abstract
2011
Conkrite, K, Sundby M, Mukai S, Thomson MJ, Mu D, Hammond SM, MacPherson D.  2011.  miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma.. Genes & development. 25(16):1734-45. Abstract