Kathleen E. Malone

Appointments and Affiliations

 
 
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Program in Epidemiology
Full Member, Appointed: 2006
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Program in Epidemiology
Program Head, Appointed: 2011
University of Washington
School of Public Health and Community Medicine
Epidemiology
Full Professor (Research), Appointed: 2007
Professional Headshot of Kathleen E. Malone

Mailing Address

Fred Hutchinson Cancer Research Center
P.O. Box 19024
M4-C308
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-4630
Fax: (206) 667-5948
kmalone@fhcrc.org

Degrees

Ph.D., University of Washington, Epidemiology, 1993.
M.P.H., Yale University, Epidemiology, 1984.
B.S.W., Temple University, Social Work, 1978.

Research Interests

The primary focus of my research is on the epidemiology of breast cancer, with foci on the etiologic and genetic determinants of developing breast cancer as well as predictors of outcomes after breast cancer, particularly second primaries, recurrences, and survival. Most of this research is interdisciplinary, links the strengths of large population-based epidemiologic studies with molecular genetics, research pathology, biostatistics, oncology, and other disciplines, and involves a large number of colleagues and staff. Investigations include studies of the risk of developing breast cancer in relation to various genetic pathways ranging from rare but high risk mutations in BRCA1/2 to more common variants in hormone-mediating genes and immune-related genes, studies of a wide spectrum of risk factors including some that are potentially modifiable, and studies of prognosis in relation to patient exposures, therapies and novel markers in tumors. The ultimate goal of these studies is to improve strategies for (1) identifying those at higher (lower) risk of developing breast cancer, and (2) reducing the risk of breast cancer, and similarly, (3) identifying those at higher (lower) risk of disease progression or second primary breast cancer, and (4) reducing risk of adverse outcomes after breast cancer.

Memberships

American Association for Cancer Research

Previous Positions

2010-2011, Co-Program Head, Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Program in Epidemiology
2002-2007, Associate Professor (Research), University of Washington, School of Public Health and Community Medicine, Department of Epidemiology
2000-2008, Associate Program Head, Fred Hutchinson Cancer Research Center, Program in Breast Cancer Research
2000-2006, Associate Member, Fred Hutchinson Cancer Research Center, Program in Epidemiology, Division of Public Health Sciences
2000-2010, Associate Program Head, Fred Hutchinson Cancer Research Center, Program in Epidemiology, Division of Public Health Sciences
1998-2000, Assistant Member, Fred Hutchinson Cancer Research Center, Epidemiology, Public Health Sciences
1998-2002, Assistant Professor (Research), University of Washington, School of Public Health and Community Medicine, Epidemiology
1994-1998, Affiliate Instructor, University of Washington, School of Public Health and Community Medicine, Epidemiology
1993-1998, Associate, Fred Hutchinson Cancer Research Center, Epidemiology, Public Health Sciences

Recent Publications

2014
Beaber, EF, Malone KE, Tang M-TC, Barlow WE, Porter PL, Daling JR, Li CI.  2014.  Oral contraceptives and breast cancer risk overall and by molecular subtype among young women.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Abstract
Ahsan, H, Halpern J, Kibriya MG, Pierce BL, Tong L, Gamazon ER, McGuire V, Felberg A, Shi J, Jasmine F et al..  2014.  A Genome-wide Association Study of Early-onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Abstract
2013
McDougall, JA, Malone KE, Daling JR, Cushing-Haugen KL, Porter PL, Li CI.  2013.  Long-Term Statin Use and Risk of Ductal and Lobular Breast Cancer among Women 55 to 74 Years of Age.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22(9):1529-37. Abstract
2012
Brooks, JD, Bernstein L, Teraoka SN, Knight JA, Mellemkjaer L, John EM, Malone KE, Reiner AS, Lynch CF, Concannon P et al..  2012.  Variation in genes related to obesity, weight and weight change and risk of contralateral breast cancer in the WECARE Study population.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 21(12):2261-2267. Abstract
2011