Polly A. Newcomb
Postdoctoral Fellow, University of Wisconsin-Madison, Cancer Biology, 1986.
Ph.D., University of Washington, Epidemiology.
M.P.H., University of Washington, Epidemiology.
As a cancer epidemiologist, the focus of my research is on the identification of modifiable risk factors for common cancers, particularly breast and colon cancer. Since many of these risk factors appear to have only modest magnitudes of effect, more precisely identifying susceptible individuals defined by genes, epigenetic changes, or personal characteristics such as body size may help direct investigations in the population, laboratory and clinic. These risk factors are also plausibly related to survival after diagnosis and several studies are examining characteristics associated with longevity.
Other interests include: the interaction of genes and the etiology of cancer; and approaches to the secondary prevention of cancer using new markers for early detection, as well as established technologies.
American Association for Cancer Research
American Society of Preventive Oncology
Society for Epidemiologic Research
The International Society for Research in Human Milk and Lactation
Honors and Awards
2009, UICC Yamagiwa-Yoshida Memoria International Cancer Study Fellowship Award, UICC
2009, Mid-Career Women Faculty Professional Development Seminar, AAMC
2009, Peggy Means Leadership Development Award, FHCRC
2010, University of Washington School of Public Health Faculty Mentor Award, University of Washington, Seattle
2002-2003, Acting Program Head, Fred Hutchinson Cancer Research Center, Cancer Prevention, Public Health Sciences
1996-1998, Associate Professor (Affiliate), University of Washington, Public Health, Epidemiology
1995-1997, Associate Member, Fred Hutchinson Cancer Research Center
1995-1999, Associate Professor, University of Wisconsin-Madison, School of Medicine and Public Health, Medicine
1994-1995, Associate Professor, University of Wisconsin-Madison, School of Medicine and Public Health, Human Oncology
1988-1994, Assistant Professor, University of Wisconsin-Madison, School of Medicine and Public Health, Human Oncology
1987-1988, Assistant Scientist, University of Wisconsin-Madison, School of Medicine and Public Health, Human Oncology
1987-1988, Assistant Scientist, University of Wisconsin-Madison, School of Medicine and Public Health, Preventive Medicine
Cadmium blood and urine concentrations as measures of exposure: NHANES 1999-2010.. Journal of exposure science & environmental epidemiology.. 2013.
Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22(11):2094-101.. 2013.
Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas.. Cancer research. 73(9):2863-72.. 2013.
Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.. 2013.
Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers? European journal of cancer (Oxford, England : 1990). 49(7):1578-87.. 2013.
Oral bisphosphonate use and colorectal cancer incidence in the Women's Health Initiative.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.. 2013.
Cancer Risks for MLH1 and MSH2 Mutation Carriers.. Human mutation. 34(3):490-7.. 2013.
Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry.. World journal of gastroenterology : WJG. 19(21):3241-8.. 2013.
Alcohol consumption before and after breast cancer diagnosis: associations with survival from breast cancer, cardiovascular disease, and other causes.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 31(16):1939-46.. 2013.
Descriptive profile of PIK3CA-mutated colorectal cancer in postmenopausal women.. International journal of colorectal disease.. 2013.
Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers.. Annals of surgical oncology. 20(6):1829-1836.. 2013.
The associations between a polygenic score, reproductive and menstrual risk factors and breast cancer risk.. Breast cancer research and treatment. 140(2):427-34.. 2013.
SBERIA: Set-Based Gene-Environment Interaction Test for Rare and Common Variants in Complex Diseases.. Genetic epidemiology. 37(5):452-64.. 2013.
Risks of colorectal and other cancers after endometrial cancer for women with lynch syndrome.. Journal of the National Cancer Institute. 105(4):274-9.. 2013.
Human papillomavirus DNA is rarely detected in colorectal carcinomas and not associated with microsatellite instability: the Seattle colon cancer family registry.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22(2):317-9.. 2013.
Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.. Human molecular genetics.. 2013.
Contribution of HIV infection to mortality among cancer patients in Uganda.. AIDS (London, England).. 2013.