Related Websites
Degrees
M.D., University of Washington, Medical Scientist Training Program, 1979.
Ph.D., University of Washington, Biological Structure, 1977.
B.S., Stanford University, Biology, 1973.
Research Interests
My program is devoted to the investigation of novel treatments for hematologic malignancies including non-Hodgkin's lymphoma and acute and chronic leukemias. We conduct basic laboratory investigations using leukemia and lymphoma cell lines and mouse xenograft models as well as human clinical trials. Agents currently under investigation include monoclonal antibodies, radioimmunoconjugates, immunotoxins, chemotherapeutic agents, and genetically modified cytotoxic T lymphocytes. In the clinical arena, we are continuing our successful program of high dose radioimmunotherapy with stem cell transplantation for B cell lymphomas and have trials planned investigating pretargeted radioimmunotherapy and gene therapy using adoptively transferred cytotoxic T lymphocytes bearing chimeric anti-CD20 receptors.
Additional Experience
Postgraduate Training in Internal Medicine:
Fellow in Oncology, University of Washington/Fred Hutchinson Cancer Research Center, 1983-1986 Chief Residency, University of Washington Medical Center, Seattle, 1982-1983 Residency, Massachusetts General Hospital, Boston, 1980-1982 Internship, Massachusetts General Hospital, Boston, 1979-1980 Board Certification: Medical Oncology Certification (A.B.I.M.), November, 1985 American Board of Internal Medicine, Sept. 15, 1982 National Board of Medical Examiners, July 1, 1980 Licensure: State of Washington, #20170 (8/6/82). Editorial Positions: Associate Editor, Journal of the National Cancer Institute, 1991-1995 Managing Editor, annals of Hematology, 1998-2001 Editor, Blood, 2001-present Editor, Journal of Therapeutic Immunology, 1995-1999 Editor, Advances in Leukemia/Lymphoma Editor, Tumor Targeting Editor, Cancer Biotherapy and Radiopharmaceuticals Editor, Cytokines, Cellular & Molecular Therapy Reviewer, Cancer Research/Clinical Cancer Research/Journal of Immunology/Journal of Clinical Oncology/Blood/Chest. Memberships
American Association for Cancer Research
American Association of Physicians
American Federation for Clinical Research, Councilor for Washington
American Medical Association
American Society for Clinical Investigation
American Society for Clinical Oncology
American Society for Gene Therapy
American Society of Hematology
Southwest Oncology Group
Honors and Awards
2009, Co-Chair, Lymphoma Steering Committee, National Cancer Institute
2007, Ellen Glesby Cohen Leadership Award, Lymphoma Research Foundation
2005, Chairman, Scientific Advisory Board, Lymphoma Research Foundation
2002, Selected as one of Seattle's 'Best Doctors', Seattle Magazine
2001-2003, Selected as one of 'America's Top Doctors',
2000, Election to the American Association of Physicians ('Old Turks'),
1998, CRS-Cygnus Award for Outstanding Work in Drug Delivery,
1996, Election to the American Society for Clinical Investigation ('Young Turks'),
1993-1995, Recipient of the first Boeing Corporate Medical Research Award,
1988-1989, Elsa Pardee Award for Cancer Research,
1987-1992, First Independent Research and Training Award from the National Institutes of Health,
1985-1986, Young Investigator Award from the American Society for Clinical Oncology,
1985-1988, Clinical Oncology Career Development Award from the American Cancer Society,
1979, PhD Thesis Honors, University of Washington
1979, Medical Auxiliary MD, PhD Award,
1979, Graduation with 'Highest Honors' from University of Washington School of Medicine,
1979, Robert S. Evans Award,
1979, John J. Bonica Prize in Anesthesiology,
1979, Lamport Biomedical Research Prize,
1979, Seattle Academy of Internal Medicine Prize,
1978, Scholarship from International College of Surgeons,
1976, Alpha Omega Alpha, Honorary Medical Fraternity (elected as 3rd year student in Spring, 1976),
1973, Phi Beta Kappa, Stanford University
1973, Departmental Honors and Departmental Distinction in Biology, Stanford University
1970-1973, George E. Gamble Honors Scholarship, Stanford University
Previous Positions
2005-2009, Clinical Research in Hematology and Hematologic Malignancies, Seattle Cancer Care Alliance
1996-2007, Biological Structure, University of Washington, Biological Structure
1993-2000, Acting Program Director, University of Washington Medical Center, High-Dose Chemotherapy Unit
1991-1996, Associate Member, Fred Hutchinson Cancer Research Center
1991-2006, Associate Director, University of Washington, Medical Scientist Training Program
1991-1996, Associate Professor in Medicine, University of Washington
1991-2006, Associate Director, Medical Scientist Training Program, University of Washington, School of Medicine
1988-1991, Adjunct Assistant Professor of Biological Structure, University of Washington
1987-1991, Assistant Professor in Medicine, University of Washington
1986-1991, Assistant Member, Fred Hutchinson Cancer Research Center
1983-1986, Senior Fellow, Fred Hutchinson Cancer Research Center
1982-1986, Acting Instructor in Medicine, University of Washington
1979-1982, Clinical Fellow in Medicine, Harvard University, Medical School
Funding
|