Mark M. Schubert
M.S.D., School of Dentistry, Oral Medicine, 1981.
Certificate, School of Dentistry, Oral Medicine, 1980.
D.D.S., University of Washington, Dentistry, 1974.
Expertise: Dr. Schubert has over 24 years of experience in the fields of oral medicine and oral oncology (i.e., oral complications of cancer and cancer therapy) and oral infectious diseases, including the oral mnaifestations and complications associated with HIV.
Current oncology research is focused on studies related to the prevention and management of oral mucositis associated with cancer therapy. Research has focused on topical anti-infectives (antibiotics and definsins), growth factors and cytokines (KGFs and IL-11), cytoprotective agents (benzydamine, amifostine), and low level lasers therapy. Additional research interests include management strategies for other oral complications of cancer therapy including salivary gland dysfunction, oral graft-versus-host disease in allogeneic hematopooeitic cell transplant recipients, and dental growth and development problems following hematopooeitic cell transplant.
Research focus in infectious disease is currently directed at determining intra oral tissues sites infected with human herpes virus 8.
Research into strategies and agents capable of reducing or preventing oral mucositis following cancer therapy have been heavily dependant on alliances between industry and clinical oncology researchers. Given the scope of the problem when combined with the need to develop FDA-approved agents, the partnering of industry with research oriented cancer care centers has been critical. The Oral Medicine Service at the SCCA is well positioned to provide the necessary expertise and clinical research environment to move these studies ahead.
(Reading, Writing, Speaking)
English: (Fluent, Fluent, Fluent)
International Society for Oral Oncology
Multinational Association of Supportive Care in Cancer
Honors and Awards
Omicron Kappa Upsilon, OKU Dental Honorary Fraternity, University of Washington
Proteomic Analysis of Saliva from Patients with Oral Chronic Graft-Versus-Host Disease.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2014.
Evaluation of Oral Beclomethasone Dipropionate for Prevention of Acute Graft-versus-Host Disease.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 18(6):922-929.. 2012.
A randomized, double-blind, placebo-controlled trial of misoprostol for oral mucositis secondary to high-dose chemotherapy.. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 20(8):1797-1804.. 2012.
A multicenter pilot evaluation of the National Institutes of Health chronic graft-versus-host disease (cGVHD) therapeutic response measures: feasibility, interrater reliability, and minimum detectable change.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(11):1619-29.. 2011.
Management of oropharyngeal mucositis pain.. Texas dental journal. 127(5):463-81.. 2010.
Oral health in cancer therapy.. Texas dental journal. 126(5):389-97,406-19,422-37.. 2009.
Oral health in cancer therapy.. Today's FDA : official monthly journal of the Florida Dental Association. 21(8):37,39-45.. 2009.
NCCN Task Force Report. prevention and management of mucositis in cancer care.. Journal of the National Comprehensive Cancer Network : JNCCN. 6 Suppl 1:S1-21;quizS22-4.. 2008.
Oral graft-versus-host disease.. Dental clinics of North America. 52(1):79-109,viii-ix.. 2008.