John A. Thompson
M.D., University of Alabama, 1979.
B.A., Davidson College, 1973.
My clinical research interests focus on the immunotherapy of cancer with cytokines and activated lymphocytes. A partial listing of trials currently under my direction include:
I serve on the National Comprehensive Cancer Network Clinical Guidelines Committees for Melanoma and Occult Primary, the Southwest Oncology Group Melanoma and Lymphoma committees, and the Cytokine Working Group. I am a member of the American Joint Committee on Cancer working group for staging of melanoma. I am the current Secretary-Treasurer of the Washington State Medical Oncology Society.
Alpha Omega Alpha, 1978
Recipient, Clinical Investigator Award (NCI), 1985-1988
American Association for Cancer Research
American Society of Clinical Oncology
Society for Biological Therapy
Southwest Oncology Group
Washington State Medical Oncology Society
1993-2004, Associate Professor, University of Washington, School of Medicine, Medicine, Oncology
1988-1993, Assistant Professor, University of Washington, Oncology
1985-1988, Acting Assistant Professor, University of Washington, Oncology
1982-1985, Fellow, University of Washington, Oncology
1982-1982, Chief Medical Resident, Providence Medical Center
1979-1982, Intern and Resident, University of Washington, Internal Medicine
Melanoma, version 4.2014.. Journal of the National Comprehensive Cancer Network : JNCCN. 12(5):621-9.. 2014.
Agents make "preferred list" in metastatic melanoma.. Journal of the National Comprehensive Cancer Network : JNCCN. 12(5 Suppl):785-7.. 2014.
A phase 2 randomised study of ramucirumab (IMC-1121B) with or without dacarbazine in patients with metastatic melanoma.. European journal of cancer (Oxford, England : 1990).. 2014.
Recombinant interleukin-21 plus sorafenib for metastatic renal cell carcinoma: a phase 1/2 study.. Journal for immunotherapy of cancer. 2:2.. 2014.
Ipilimumab administration in patients with advanced melanoma and hepatitis B and C.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 31(21):e370-2.. 2013.
Melanoma, version 2.2013: featured updates to the NCCN guidelines.. Journal of the National Comprehensive Cancer Network : JNCCN. 11(4):395-407.. 2013.
Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype.. Proceedings of the National Academy of Sciences of the United States of America. 109(12):4592-7.. 2012.
Melanoma.. Journal of the National Comprehensive Cancer Network : JNCCN. 10(3):366-400.. 2012.
Systemic therapy for metastatic melanoma in 2012: dawn of a new era.. Journal of the National Comprehensive Cancer Network : JNCCN. 10(3):403-12.. 2012.
Ipilimumab in Treatment-naive and Previously Treated Patients with Metastatic Melanoma: Retrospective Analysis of Efficacy and Safety Data from a Phase II Trial.. Journal of immunotherapy (Hagerstown, Md. : 1997). 35(1):73-77.. 2012.
Ten years of progress in melanoma.. Journal of the National Comprehensive Cancer Network : JNCCN. 10(8):932-5.. 2012.
Randomized Phase II Trial of Sunitinib on an Intermittent Versus Continuous Dosing Schedule As First-Line Therapy for Advanced Renal Cell Carcinoma.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 30(12):1371-7.. 2012.
Allogeneic hematopoietic cell transplantation for renal cell carcinoma: ten years after.. Expert opinion on biological therapy. 11(6):763-73.. 2011.
Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032).. European journal of cancer (Oxford, England : 1990). 47(10):1476-83.. 2011.
Phase I Trial of ALT-801, an Interleukin-2/T-Cell Receptor Fusion Protein Targeting p53 (aa264-272)/HLA-A*0201 Complex, in Patients with Advanced Malignancies.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17(24):7765-7775.. 2011.
Refractory colitis following anti-CTLA4 antibody therapy: analysis of mucosal FOXP3+ T cells.. Digestive diseases and sciences. 55(5):1396-405.. 2010.
Treatment of metastatic melanoma: an overview.. Oncology (Williston Park, N.Y.). 23(6):488-96.. 2009.
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1.. The New England journal of medicine. 358(25):2698-703.. 2008.
Development of modified vaccinia Ankara-5T4 as specific immunotherapy for advanced human cancer.. Expert opinion on biological therapy. 8(12):1947-53.. 2008.
C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients.. Clinical cancer research : an official journal of the American Association for Cancer Research. 14(16):5260-9.. 2008.