Yingye Zheng

Appointments and Affiliations
 
 
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Biostatistics & Biomathematics
Associate Member, Appointed: 2007
University of Washington
School of Public Health and Community Medicine
Biostatistics
Affiliate Associate Professor, Appointed: 2008
 Professional Headshot of Yingye Zheng

Mailing Address

1100 Fairview Ave. N.
M2-B500
P.O. Box 19024
Seattle, Washington 98109-1024
United States

Contact

Phone: (206) 667-7580
Fax: (206) 667-7004
yzheng@fhcrc.org

Degrees

Ph.D., University of Washington, Biostatistics, 2002.
M.S., University of Washington, Biostatistics, 1999.
M.A., Washington University in St. Louis, Psychology, 1997.
B.S., Peking University, Psychology, 1992.

Research Interests

My research interests have been in the statistical methods for longitudinal data with time-to-event outcome, with a focus on using semi-parametric methods for estimating time-dependent ROC curves which are useful for evaluating the ability of longitudinal biomarkers or algorithms to identify cancer early, or signal disease prognosis. I am also interested in statistical methods for family-based genetic association studies. I am presently providing support to a number of research proposals and applications in the cancer prevention research program, including serving as an investigator in the DMCC of the Early Detection Research Network.

Languages

(Reading, Writing, Speaking)

Chinese, Mandarin: (Fluent, Fluent, Fluent)
English: (Fluent, Fluent, Fluent)

Honors and Awards

2006, Best Paper in Biometrics during 2004-2005, award selection by journal editors, International Biometeric Society
2003, Senior Biostatistics Student Award, University of Washington
1996, Division 20 'Completed Research Competition' Award, American Psychological Association
1994-1995, Merit Based Graduate Fellowship, Washington University
1989-1990, GuangHua Award for Academic Excellence, Peking University

Previous Positions

2002-2008, Affiliate Assistant Professor, University of Washington, School of Public Health and Community Medicine, Biostatistics
2002-2007, Assistant Member, Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Cancer Prevention Research Program
2000-2002, Dissertation Research, University of Washington, School of Public Health and Community Medicine, Biostatistics
1997-2002, Research Assistant, Group Health Cooperative, Center for Health Studies
1996-1997, Teaching Assistant, University of Washington, College of Arts and Sciences, Psychology
1995-1997, Research Assistant, University of Washington, Aging and Develpment Program, Psychology

 

Recent Publications

2013
Sun, J, Zheng Y, Hsu L.  2013.  A unified mixed-effects model for rare-variant association in sequencing studies.. Genetic epidemiology. 37(4):334-44. Abstract
Feng, Z, Kagan J, Pepe M, Thornquist M, Ann Rinaudo J, Dahlgren J, Krueger K, Zheng Y, Patriotis C, Huang Y et al..  2013.  The Early Detection Research Network's Specimen Reference Sets: Paving the Way for Rapid Evaluation of Potential Biomarkers.. Clinical chemistry. 59(1):68-74. Abstract
Zschäbitz, S, Cheng T-YD, Neuhouser ML, Zheng Y, Ray RM, Miller JW, Song X, Maneval DR, Beresford SAA, Lane D et al..  2013.  B vitamin intakes and incidence of colorectal cancer: results from the Women's Health Initiative Observational Study cohort.. The American journal of clinical nutrition. 97(2):332-43. Abstract
Miller, JW, Beresford SAA, Neuhouser ML, Cheng T-YD, Song X, Brown EC, Zheng Y, Rodriguez B, Green R, Ulrich CM.  2013.  Homocysteine, cysteine, and risk of incident colorectal cancer in the Women's Health Initiative observational cohort.. The American journal of clinical nutrition. 97(4):827-34. Abstract
2012
Toriola, AT, Cheng T-YD, Neuhouser ML, Wener MH, Zheng Y, Brown E, Miller JW, Song X, Beresford SAA, Gunter MJ et al..  2012.  Biomarkers of inflammation are associated with colorectal cancer risk in women but are not suitable as early detection markers.. International journal of cancer. Journal international du cancer. Abstract
Zheng, Y, Cai T, Jin Y, Feng Z.  2012.  Evaluating Prognostic Accuracy of Biomarkers under Competing Risk.. Biometrics. 68(2):388-396. Abstract
Cai, T, Zheng Y.  2012.  Evaluating prognostic accuracy of biomarkers in nested case-control studies.. Biostatistics (Oxford, England). 13(1):89-100. Abstract
Zhou, QM, Zheng Y, Cai T.  2012.  Subgroup specific incremental value of new markers for risk prediction.. Lifetime data analysis. Abstract
Liu, D, Cai T, Zheng Y.  2012.  Evaluating the predictive value of biomarkers with stratified case-cohort design.. Biometrics. 68(4):1219-27. Abstract
2011
Makawita, S, Smith C, Batruch I, Zheng Y, Rückert F, Grützmann R, Pilarsky C, Gallinger S, Diamandis EP.  2011.  Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers.. Molecular & cellular proteomics : MCP. 10(10):M111.008599. Abstract
Passarelli, MN, Coghill AE, Hutter CM, Zheng Y, Makar KW, Potter JD, Newcomb PA.  2011.  Common colorectal cancer risk variants in SMAD7 are associated with survival among prediagnostic nonsteroidal anti-inflammatory drug users: a population-based study of postmenopausal women.. Genes, chromosomes & cancer. 50(11):875-86. Abstract
Coghill, AE, Newcomb PA, Chia VM, Zheng Y, Wernli KJ, Passarelli MN, Potter JD.  2011.  Pre-diagnostic NSAID use but not hormone therapy is associated with improved colorectal cancer survival in women.. British journal of cancer. 104(5):763-8. Abstract
Cai, T, Gerds TA, Zheng Y, Chen J.  2011.  Robust prediction of t-year survival with data from multiple studies.. Biometrics. 67(2):436-44. Abstract
Tamers, SL, Beresford SAA, Cheadle AD, Zheng Y, Bishop SK, Thompson B.  2011.  The association between worksite social support, diet, physical activity and body mass index.. Preventive medicine. 53(1-2):53-6. Abstract
Tamers, SL, Beresford SAA, Thompson B, Zheng Y, Cheadle AD.  2011.  Exploring the role of co-worker social support on health care utilization and sickness absence.. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine. 53(7):751-7. Abstract
Navarro, SL, Saracino MR, Makar KW, Thomas SS, Li L, Zheng Y, Levy L, Schwarz Y, Bigler J, Potter JD et al..  2011.  Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases.. Journal of nutrigenetics and nutrigenomics. 4(2):110-8. Abstract
2010
Kuk, C, Gunawardana GC, Soosaipillai A, Kobayashi H, Li L, Zheng Y, Diamandis EP.  2010.  Nidogen-2: a new serum biomarker for ovarian cancer.. Clinical biochemistry. 43(4-5):355-61. Abstract
Zheng, Y, Cai T, Stanford JL, Feng Z.  2010.  Semiparametric models of time-dependent predictive values of prognostic biomarkers.. Biometrics. 66(1):50-60. Abstract
Cai, T, Gerds TA, Zheng Y, Chen J.  2010.  Robust Prediction of t-Year Survival with Data from Multiple Studies.. Biometrics. Abstract
Zheng, Y, Heagerty PJ, Hsu L, Newcomb PA.  2010.  On combining family-based and population-based case-control data in association studies.. Biometrics. 66(4):1024-33. Abstract
Wernli, KJ, Newcomb PA, Wang Y, Makar KW, Shadman M, Chia VM, Burnett-Hartman A, Wurscher MA, Zheng Y, Mandelson MT.  2010.  Body size, IGF and growth hormone polymorphisms, and colorectal adenomas and hyperplastic polyps.. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 20(4):305-9. Abstract
Holmes, RS, Zheng Y, Baron JA, Li L, McKeown-Eyssen G, Newcomb PA, Stern MC, Haile RW, Grady WM, Potter JD et al..  2010.  Use of folic acid-containing supplements after a diagnosis of colorectal cancer in the Colon Cancer Family Registry.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 19(8):2023-34. Abstract
2009
Jin, Z, Cheng Y, Gu W, Zheng Y, Sato F, Mori Y, Olaru AV, Paun BC, Yang J, Kan T et al..  2009.  A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus.. Cancer research. 69(10):4112-5. Abstract
Bapat, B, Lindor NM, Baron J, Siegmund K, Li L, Zheng Y, Haile R, Gallinger S, Jass JR, Young JP et al..  2009.  The association of tumor microsatellite instability phenotype with family history of colorectal cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 18(3):967-75. Abstract
Kulasingam, V, Zheng Y, Soosaipillai A, Leon AE, Gion M, Diamandis EP.  2009.  Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer.. International journal of cancer. Journal international du cancer. 125(1):9-14. Abstract