Center-Authored Papers

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A
Aplenc, R, Alonzo TA, Gerbing RB, Lange BJ, Hurwitz CA, Wells RJ, Bernstein ID, Buckley P, Krimmel K, Smith FO et al..  2008.  Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(14):2390-3295. Abstract
B
Bernstein, ID, Delaney C.  2012.  Engineering stem cell expansion.. Cell stem cell. 10(2):113-4. Abstract
Butler, JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M et al..  2010.  Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.. Cell stem cell. 6(3):251-64. Abstract
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Dahlberg, A, Delaney C, Bernstein ID.  2011.  Ex vivo expansion of human hematopoietic stem and progenitor cells.. Blood. 117(23):6083-90. Abstract
Dayyani, F, Wang J, Yeh J-RJ, Ahn E-Y, Tobey E, Zhang D-E, Bernstein ID, Peterson RT, Sweetser DA.  2008.  Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.. Blood. 111(8):4338-47. Abstract
Delaney, C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID.  2010.  Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.. Nature medicine. 16(2):232-6. Abstract
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Gutman, JA, Turtle CJ, Manley TJ, Heimfeld S, Bernstein ID, Riddell SR, Delaney C.  2010.  Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.. Blood. 115(4):757-65. Abstract
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Hadland, BK, Bernstein ID.  2013.  Visualizing human ESC-derived hematopoiesis.. Blood. 121(5):717-8. Abstract
Ho, PA, Kopecky KJ, Alonzo TA, Gerbing RB, Miller KL, Kuhn J, Zeng R, Ries RE, Raimondi SC, Hirsch BA et al..  2011.  Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric/adult AML: a report from the Children's Oncology Group and SWOG.. Blood. 118(17):4561-6. Abstract
Ho, PA, Alonzo TA, Kopecky KJ, Miller KL, Kuhn J, Zeng R, Gerbing RB, Raimondi SC, Hirsch BA, Oehler VG et al..  2010.  Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 24(5):909-13. Abstract
L
Laurenti, E, Varnum-Finney B, Wilson A, Ferrero I, Blanco-Bose WE, Ehninger A, Knoepfler PS, Cheng P-F, MacDonald RH, Eisenman RN et al..  2008.  Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.. Cell stem cell. 3(6):611-24. Abstract
Leko, V, Varnum-Finney B, Li H, Gu Y, Flowers D, Nourigat C, Bernstein ID, Bedalov A.  2012.  SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.. Blood. 119(8):1856-1860. Abstract
M
Minella, AC, Loeb KR, Knecht A, Welcker M, Varnum-Finney BJ, Bernstein ID, Roberts JM, Clurman BE.  2008.  Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.. Genes & development. 22(12):1677-89. Abstract
P
Parcelier, A, Maharzi N, Delord M, Robledo-Sarmiento M, Nelson E, Belakhdar-Mekid H, Pla M, Kuranda K, Parietti V, Goodhardt M et al..  2011.  AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.. Blood. 118(7):1784-96. Abstract
Parker, MH, Loretz C, Tyler AE, Duddy WJ, Hall JK, Olwin BB, Bernstein ID, Storb R, Tapscott SJ.  2012.  Activation of Notch Signaling During ex vivo Expansion Maintains Donor Muscle Cell Engraftment.. Stem cells (Dayton, Ohio). Abstract
Pollard, JA, Alonzo TA, Gerbing RB, Ho PA, Zeng R, Ravindranath Y, Dahl G, Lacayo NJ, Becton D, Chang M et al..  2010.  Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML.. Blood. 115(12):2372-9. Abstract
Pollard, JA, Alonzo TA, Loken M, Gerbing RB, Ho PA, Bernstein ID, Raimondi SC, Hirsch B, Franklin J, Walter RB et al..  2012.  Correlation of CD33 expression level with disease characteristics and response to gemtuzumab ozogamicin containing chemotherapy in childhood AML.. Blood. Abstract
V
Van de Walle, I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID et al..  2011.  Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.. Blood. 117(17):4449-59. Abstract
Varnum-Finney, B, Dallas MH, Kato K, Bernstein ID.  2008.  Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus.. Blood. 111(5):2615-20. Abstract
Varnum-Finney, B, Halasz LM, Sun M, Gridley T, Radtke F, Bernstein ID.  2011.  Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.. The Journal of clinical investigation. 121(3):1207-16. Abstract
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Walter, RB, Boyle KM, Appelbaum FR, Bernstein ID, Pagel JM.  2008.  Simultaneously targeting CD45 significantly increases cytotoxicity of the anti-CD33 immunoconjugate, gemtuzumab ozogamicin, against acute myeloid leukemia (AML) cells and improves survival of mice bearing human AML xenografts.. Blood. 111(9):4813-6. Abstract
Walter, RB, Raden BW, Zeng R, Häusermann P, Bernstein ID, Cooper JA.  2008.  ITIM-dependent endocytosis of CD33-related Siglecs: role of intracellular domain, tyrosine phosphorylation, and the tyrosine phosphatases, Shp1 and Shp2.. Journal of leukocyte biology. 83(1):200-11. Abstract
Walter, RB, Häusermann P, Raden BW, Teckchandani AM, Kamikura DM, Bernstein ID, Cooper JA.  2008.  Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor.. Traffic (Copenhagen, Denmark). 9(2):267-79. Abstract
Watts, KL, Delaney C, Humphries KR, Bernstein ID, Kiem H-P.  2010.  Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells.. Blood. 116(26):5859-66. Abstract
Y
Yang, Q, Kardava L, St Leger A, Martincic K, Varnum-Finney B, Bernstein ID, Milcarek C, Borghesi L.  2008.  E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.. Journal of immunology (Baltimore, Md. : 1950). 181(9):5885-94. Abstract