Center-Authored Papers

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Cai, C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, Marck B, Matsumoto AM, Simon N, Wang H et al..  2011.  Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration Resistant Prostate Cancer and is Upregulated by Treatment with CYP17A1 Inhibitors.. Cancer research. 71(20):6503-13. Abstract
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Green, SM, Mostaghel EA, Nelson PS.  2012.  Androgen action and metabolism in prostate cancer.. Molecular and cellular endocrinology. Abstract
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Harris, WP, Mostaghel EA, Nelson PS, Montgomery B.  2009.  Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion.. Nature clinical practice. Urology. 6(2):76-85. Abstract
Hu, R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E et al..  2012.  Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.. Cancer research. 72(14):3457-62. Abstract
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Marks, LS, Mostaghel EA, Nelson PS.  2008.  Prostate tissue androgens: history and current clinical relevance.. Urology. 72(2):247-54. Abstract
Mendiratta, P, Mostaghel EA, Guinney J, Tewari AK, Porrello A, Barry WT, Nelson PS, Febbo PG.  2009.  Genomic strategy for targeting therapy in castration-resistant prostate cancer.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(12):2022-9. Abstract
Meng, J, Mostaghel EA, Vakar-Lopez F, Montgomery B, True L, Nelson PS.  2011.  Testosterone regulates tight junction proteins and influences prostatic autoimmune responses.. Hormones & cancer. 2(3):145-56. Abstract
Montgomery, BR, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD, Nelson PS.  2008.  Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth.. Cancer research. 68(11):4447-54. Abstract
Mostaghel, EA, Wright JL, Montgomery B, Stanford JL.  2011.  SLCO Transport Genes in Prostate Cancer--Response.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 20(10):2326-7.
Mostaghel, EA, Nelson PS.  2008.  Intracrine androgen metabolism in prostate cancer progression: mechanisms of castration resistance and therapeutic implications.. Best practice & research. Clinical endocrinology & metabolism. 22(2):243-58. Abstract
Mostaghel, EA, Geng L, Holcomb I, Coleman IM, Lucas J, True LD, Nelson PS.  2010.  Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention.. Cancer research. 70(4):1286-95. Abstract
Mostaghel, EA, Marck BT, Plymate SR, Vessella RL, Balk S, Matsumoto AM, Nelson PS, Montgomery BR.  2011.  Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17(18):5913-25. Abstract
Mostaghel, EA, Lin DW, Amory JK, Wright JL, Marck BT, Nelson PS, Matsumoto AM, Bremner WJ, Page ST.  2012.  Impact of Male Hormonal Contraception on Prostate Androgens and Androgen Action in Healthy Men: A Randomized, Controlled Trial.. The Journal of clinical endocrinology and metabolism. Abstract
Mostaghel, EA, Plymate S.  2011.  New hormonal therapies for castration-resistant prostate cancer.. Endocrinology and metabolism clinics of North America. 40(3):625-42,x. Abstract
Mostaghel, EA, Montgomery B, Nelson PS.  2009.  Castration-resistant prostate cancer: targeting androgen metabolic pathways in recurrent disease.. Urologic oncology. 27(3):251-7. Abstract
Mostaghel, EA, Solomon KR, Pelton K, Freeman MR, Montgomery BR.  2012.  Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors.. PloS one. 7(1):e30062. Abstract
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Page, ST, Lin DW, Mostaghel EA, Marck BT, Wright JL, Wu J, Amory JK, Nelson PS, Matsumoto AM.  2011.  Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial.. The Journal of clinical endocrinology and metabolism. 96(2):430-7. Abstract
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Sun, S, Sprenger CCT, Vessella RL, Haugk K, Soriano K, Mostaghel EA, Page ST, Coleman IM, Nguyen HM, Sun H et al..  2010.  Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant.. The Journal of clinical investigation. 120(8):2715-30. Abstract
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Wang, D, Montgomery BR, Schmidt LJ, Mostaghel EA, Huang H, Nelson PS, Tindall DJ.  2009.  Reduced tumor necrosis factor receptor-associated death domain expression is associated with prostate cancer progression.. Cancer research. 69(24):9448-56. Abstract
Wright, JL, Kwon EM, Ostrander EA, Montgomery BR, Lin DW, Vessella R, Stanford JL, Mostaghel EA.  2011.  Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomes.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 20(4):619-27. Abstract